Version 1.0

Classification of proteins into one of four possible classes



Pasquier, C., Promponas, V. and Hamodrakas, S.J.
Department of Cell Biology and Biophysics,
Faculty of Biology, University of Athens
Panepistimiopolis, Kouponia, Athens 15701, Greece

PRED-CLASS is a system of cascading neural networks that classifies any protein, given its aminoacid sequence alone, into one of four possible classes:

The results obtained on several test sets are summarized in the table below :

type of proteinsnumber of sequencespercentage classified in...
the membrane protein classthe fibrous protein classthe globular protein classthe mixed protein class
membrane
147
139 (94.5%)
  0  (0.0%)
  8 (5.4%)
  0   (0.0%)
fibrous
 73
  1   (1.4%)
  72  (98.6%)
 0 (0.0%)
  0   (0.0%)
globular
 55
  0  (0.0%)
 1  (1.8%)
  54 (98.2%)
  0   (0.0%)
mixed
112
  3   (2.7%)
  3   (2.7%)
  0 (0.0%)
106  (94.6%)

A paper describing the neural network system has been submitted to Proteins


Now, you can :

Run PRED-CLASS on a sequence

Browse detailed results obtained with the algorithm on several test sets

View lists of data used to train and evaluate PRED-CLASS

Go to the Biophysics Lab Homepage





Claude Pasquier